Transdermal 17beta-estradiol for preventing postmenopausal bone loss.
نویسندگان
چکیده
منابع مشابه
A clinical trial of 3 doses of transdermal 17beta-estradiol for preventing postmenopausal bone loss: a preliminary study.
BACKGROUND It is well documented that a daily oral dose of 0.625 mg of conjugated equine estrogen or 1-2 mg of 17beta-estradiol is needed to prevent postmenopausal bone loss. Recent studies have indicated that a lower dose of estrogen maybe as effective in maintaining bone mass. The purpose of this study was to evaluate the effects of 3 dosages of transdermally administered 17beta-estradiol gel...
متن کاملAge moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women.
OBJECTIVE We evaluated age and coronary heart disease (CHD) as potential moderators of the effects of 17beta-estradiol on vascular endothelial function in postmenopausal women. METHODS AND RESULTS In a double-blind crossover design, 100 postmenopausal women aged 50 to 80 years were randomized to each of 3 transdermal patches, releasing 17beta-estradiol (0.05 mg/d), 17beta-estradiol (0.05 mg/d...
متن کاملDouble-blind randomized placebo-controlled study of transdermal estrogen replacement therapy on hypertensive postmenopausal women.
We investigated the effects of transdermal 17beta-estradiol, combined with standard antihypertensive therapy, on the modification of the cardiovascular risk profile in hypertensive postmenopausal women. In a randomized, double-blind, placebo-controlled study, we enrolled 200 postmenopausal women with mild to moderate hypertension. Patients received 17beta-estradiol (50 microg/day, transdermal) ...
متن کاملEffects of transdermal 17beta-estradiol on left ventricular anatomy and performance in hypertensive women.
To reduce cardiovascular complications, antihypertensive therapy should not only normalize blood pressure but also induce a regression of structural abnormalities, which are the expression of end-organ damage. We investigated the effects of transdermal 17beta-estradiol, combined with standard antihypertensive therapy, on the modification of left ventricular anatomy and systolic performance in h...
متن کاملEffects of ultralow-dose transdermal estradiol on bone mineral density: a randomized clinical trial.
OBJECTIVE Because small increments in levels of endogenous plasma estradiol are associated with higher postmenopausal bone mineral density, we investigated the safety and effectiveness in preventing bone loss of unopposed, very-low-dose transdermal estradiol for postmenopausal women. METHODS This was a randomized, placebo-controlled, double-blind trial with 2-year follow-up at 9 United States...
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ورودعنوان ژورنال:
- Journal of the Chinese Medical Association : JCMA
دوره 70 10 شماره
صفحات -
تاریخ انتشار 2007